| EIF3B | |||||||||||||||||||||||||||||||||||||||||||||||||||
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| Identifiers | |||||||||||||||||||||||||||||||||||||||||||||||||||
| Aliases | EIF3B, EIF3-ETA, EIF3-P110, EIF3-P116, EIF3S9, PRT1, eukaryotic translation initiation factor 3 subunit B | ||||||||||||||||||||||||||||||||||||||||||||||||||
| External IDs | OMIM: 603917; MGI: 106478; HomoloGene: 2780; GeneCards: EIF3B; OMA:EIF3B - orthologs | ||||||||||||||||||||||||||||||||||||||||||||||||||
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| Wikidata | |||||||||||||||||||||||||||||||||||||||||||||||||||
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Eukaryotic translation initiation factor 3 subunit B (eIF3b) is a protein that in humans is encoded by the EIF3B gene.[5][6]
Interactions
EIF3B has been shown to interact with P70-S6 Kinase 1[7] and EIF3A.[5][8][9][10]
See also
References
- 1 2 3 GRCh38: Ensembl release 89: ENSG00000106263 – Ensembl, May 2017
- 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000056076 – Ensembl, May 2017
- ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- 1 2 Méthot N, Rom E, Olsen H, Sonenberg N (February 1997). "The human homologue of the yeast Prt1 protein is an integral part of the eukaryotic initiation factor 3 complex and interacts with p170". Journal of Biological Chemistry. 272 (2): 1110–1116. doi:10.1074/jbc.272.2.1110. PMID 8995410.
- ↑ "Entrez Gene: EIF3S9 eukaryotic translation initiation factor 3, subunit 9 eta, 116kDa".
- ↑ Holz MK, Ballif BA, Gygi SP, Blenis J (November 2005). "mTOR and S6K1 mediate assembly of the translation preinitiation complex through dynamic protein interchange and ordered phosphorylation events". Cell. 123 (4): 569–580. doi:10.1016/j.cell.2005.10.024. PMID 16286006. S2CID 11118504.
- ↑ Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (October 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". European Journal of Biochemistry. 270 (20): 4133–4139. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
- ↑ Harris TE, Chi A, Shabanowitz J, Hunt DF, Rhoads RE, Lawrence JC (April 2006). "mTOR-dependent stimulation of the association of eIF4G and eIF3 by insulin". The EMBO Journal. 25 (8): 1659–1668. doi:10.1038/sj.emboj.7601047. PMC 1440840. PMID 16541103.
- ↑ Block KL, Vornlocher HP, Hershey JW (November 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". Journal of Biological Chemistry. 273 (48): 31901–31908. doi:10.1074/jbc.273.48.31901. PMID 9822659.
Further reading
- Kirken RA, Rui H, Evans GA, Farrar WL (Oct 1993). "Characterization of an interleukin-2 (IL-2)-induced tyrosine phosphorylated 116-kDa protein associated with the IL-2 receptor beta-subunit". Journal of Biological Chemistry. 268 (30): 22765–22770. doi:10.1016/S0021-9258(18)41592-X. PMID 7693677.
- Bonaldo MF, Lennon G, Soares MB (Sep 1996). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Research. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
- Asano K, Kinzy TG, Merrick WC, Hershey JW (Jan 1997). "Conservation and diversity of eukaryotic translation initiation factor eIF3". Journal of Biological Chemistry. 272 (2): 1101–1109. doi:10.1074/jbc.272.2.1101. PMID 8995409.
- Chaudhuri J, Chakrabarti A, Maitra U (Dec 1997). "Biochemical characterization of mammalian translation initiation factor 3 (eIF3). Molecular cloning reveals that p110 subunit is the mammalian homologue of Saccharomyces cerevisiae protein Prt1". Journal of Biological Chemistry. 272 (49): 30975–30983. doi:10.1074/jbc.272.49.30975. PMID 9388245.
- Block KL, Vornlocher HP, Hershey JW (Nov 1998). "Characterization of cDNAs encoding the p44 and p35 subunits of human translation initiation factor eIF3". Journal of Biological Chemistry. 273 (48): 31901–31908. doi:10.1074/jbc.273.48.31901. PMID 9822659.
- The Sanger Centre, The Washington University Genome Sequencing Cente (Nov 1998). "Toward a complete human genome sequence". Genome Research. 8 (11): 1097–1108. doi:10.1101/gr.8.11.1097. PMID 9847074.
- Lin L, Holbro T, Alonso G, Gerosa D, Burger MM (2001). "Molecular interaction between human tumor marker protein p150, the largest subunit of eIF3, and intermediate filament protein K7". Journal of Cellular Biochemistry. 80 (4): 483–490. doi:10.1002/1097-4644(20010315)80:4<483::AID-JCB1002>3.0.CO;2-B. PMID 11169732. S2CID 35848129.
- Asano K, Shalev A, Phan L, Nielsen K, Clayton J, Valásek L, et al. (May 2001). "Multiple roles for the C-terminal domain of eIF5 in translation initiation complex assembly and GTPase activation". The EMBO Journal. 20 (9): 2326–2337. doi:10.1093/emboj/20.9.2326. PMC 125443. PMID 11331597.
- Mayeur GL, Fraser CS, Peiretti F, Block KL, Hershey JW (Oct 2003). "Characterization of eIF3k: a newly discovered subunit of mammalian translation initiation factor elF3". European Journal of Biochemistry. 270 (20): 4133–4139. doi:10.1046/j.1432-1033.2003.03807.x. PMID 14519125.
- Fraser CS, Lee JY, Mayeur GL, Bushell M, Doudna JA, Hershey JW (Mar 2004). "The j-subunit of human translation initiation factor eIF3 is required for the stable binding of eIF3 and its subcomplexes to 40 S ribosomal subunits in vitro". Journal of Biological Chemistry. 279 (10): 8946–8956. doi:10.1074/jbc.M312745200. PMID 14688252.
- Beausoleil SA, Jedrychowski M, Schwartz D, Elias JE, Villén J, Li J, et al. (Aug 2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proceedings of the National Academy of Sciences of the United States of America. 101 (33): 12130–12135. Bibcode:2004PNAS..10112130B. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
- Rush J, Moritz A, Lee KA, Guo A, Goss VL, Spek EJ, et al. (Jan 2005). "Immunoaffinity profiling of tyrosine phosphorylation in cancer cells". Nature Biotechnology. 23 (1): 94–101. doi:10.1038/nbt1046. PMID 15592455. S2CID 7200157.
- Olsen JV, Blagoev B, Gnad F, Macek B, Kumar C, Mortensen P, et al. (Nov 2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–648. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.
- ElAntak L, Tzakos AG, Locker N, Lukavsky PJ (Mar 2007). "Structure of eIF3b RNA recognition motif and its interaction with eIF3j: structural insights into the recruitment of eIF3b to the 40 S ribosomal subunit" (PDF). Journal of Biological Chemistry. 282 (11): 8165–8174. doi:10.1074/jbc.M610860200. PMID 17190833. S2CID 2313046.
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