Fedrilate

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Wikipedia

Fedrilate
Clinical data
Trade namesTussefan
ATC code
Identifiers
  • 4-morpholin-4-ylbutan-2-yl 4-phenyloxane-4-carboxylate
CAS Number
PubChem CID
ChemSpider
UNII
KEGG
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.041.390 Edit this at Wikidata
Chemical and physical data
FormulaC20H29NO4
Molar mass347.455 g·mol−1
3D model (JSmol)
  • O=C(OC(CCN1CCOCC1)C)C3(c2ccccc2)CCOCC3
  • InChI=1S/C20H29NO4/c1-17(7-10-21-11-15-24-16-12-21)25-19(22)20(8-13-23-14-9-20)18-5-3-2-4-6-18/h2-6,17H,7-16H2,1H3 checkY
  • Key:RDEOYUSTRWNWLX-UHFFFAOYSA-N checkY
  (verify)

Fedrilate is a centrally acting cough suppressant. It was patented as a mucolytic by UCB in 1971, but was never brought to market in the US.[1] In the Netherlands, it has been marketed as Tussefan and in combination with guaifenesin as Tussefan expectorans.[2]

References

  1. ↑ US patent 3567835, Henri Morren, "Mucolytic salts, compositions and process for treating mucus", issued March 2, 1971
  2. ↑ Kok J, Oosterveld WJ, Sibilo SR (1979). Pharmacotherapeutisch Vademecum (in Dutch). Bussum: Romen. ISBN 90-228-8006-0.