GPR88

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Wikipedia

GPR88
Identifiers
AliasesGPR88, STRG, COCPMR, G protein-coupled receptor 88
External IDsOMIM: 607468; MGI: 1927653; HomoloGene: 11104; GeneCards: GPR88; OMA:GPR88 - orthologs
Orthologs
SpeciesHumanMouse
Entrez

54112

64378

Ensembl

ENSG00000181656

ENSMUSG00000068696

UniProt

Q9GZN0

Q9EPB7

RefSeq (mRNA)

NM_022049

NM_022427

RefSeq (protein)

NP_071332

NP_071872

Location (UCSC)Chr 1: 100.54 – 100.54 MbChr 3: 116.04 – 116.05 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Probable G-protein coupled receptor 88 is a protein that in humans is encoded by the GPR88 gene.[5][6][7][8][9]

Ligands

Agonists

References

  1. 1 2 3 GRCh38: Ensembl release 89: ENSG00000181656 – Ensembl, May 2017
  2. 1 2 3 GRCm38: Ensembl release 89: ENSMUSG00000068696 – Ensembl, May 2017
  3. ↑ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ↑ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ↑ Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
  6. ↑ Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
  7. ↑ Mizushima K, Miyamoto Y, Tsukahara F, et al. (2001). "A novel G-protein-coupled receptor gene expressed in striatum". Genomics. 69 (3): 314–21. doi:10.1006/geno.2000.6340. PMID 11056049.
  8. ↑ Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  9. ↑ Van Waes V, Tseng K, Steiner H (2011). "GPR88 - a putative signaling molecule predominantly expressed in the striatum: Cellular localization and developmental regulation". Basal Ganglia. 1 (2): 83–89. doi:10.1016/j.baga.2011.04.001. PMC 3144573. PMID 21804954.
  10. ↑ Rahman MT, Decker AM, Ben Hamida S, Perrey DA, Chaminda Lakmal HH, Maitra R, Darcq E, Kieffer BL, Jin C (Feb 2023). "Improvement of the Metabolic Stability of GPR88 Agonist RTI-13951-33: Design, Synthesis, and Biological Evaluation". J Med Chem. 66 (4): 2964–2978. doi:10.1021/acs.jmedchem.2c01983. PMC 9974843. PMID 36749855.{{cite journal}}: CS1 maint: multiple names: authors list (link)