Flufenauxirim

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Wikipedia

Flufenauxirim
Skeletal formula of flufenauxirim
Skeletal formula of flufenauxirim
Names
Preferred IUPAC name
6-amino-2-[2-fluoro-3-methoxy-4-(trifluoromethyl)phenyl]-5-methoxypyrimidine-4-carboxylic acid
Other names
Flufenauxirime
Identifiers
3D model (JSmol)
  • InChI=1S/C14H11F4N3O4/c1-24-9-6(14(16,17)18)4-3-5(7(9)15)12-20-8(13(22)23)10(25-2)11(19)21-12/h3-4H,1-2H3,(H,22,23)(H2,19,20,21)
    Key: WNQNYSQIBVZMHA-UHFFFAOYSA-N
  • COC1=C(C=CC(=C1F)C2=NC(=C(C(=N2)N)OC)C(=O)O)C(F)(F)F
Properties
C14H11F4N3O4
Molar mass 361.253 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).

Flufenauxirim is a chemical herbicide. It is a pyrimidinecarboxylic acid and a broad-spectrum herbicide.[1][2] Its mechanism of action is unclear, but likely involves inhibition of enzymes that are involved in synthesis of fatty acids and amino acids.[1] The formula of flufenauxirim is C14H11F4N3O4.[3][4]

The herbicide was announced in March 2025 as a product of Chinese company Qingdao KingAgroot Chemical Compound Co., and was provisionally approved by the International Organization for Standardization.[2] It is noted as being effective against grasses and broadleaf weeds.[3] As of August 2025, it is not approved by any European regulatory authority.[1]

Production and synthesis

Flufenauxirim is produced through a substitution reaction between pyrimidine and an aromatic intermediate that is substituted with methoxy and fluorine groups.[1] A derivative of flufenauxirim is flufenauxirim-metotyl.[5]

References

  1. 1 2 3 4 "Flufenauxirim". PPDB: Pesticide Properties DataBase. University of Hertfordshire. August 20, 2025. Retrieved August 21, 2025.
  2. 1 2 Shan, Mickey (March 31, 2025). "Flufenauxirim - A new common name for a pyrimidinecarboxylic acid herbicide from Qingdao KingAgroot provisionally approved by ISO". Agropages. Retrieved August 21, 2025.
  3. 1 2 "New ISO March 2025: Flufenauxirim Herbicide from Chinese Player Qingdao KingAgroot Chemical". ChemRobotics Times. March 30, 2025. Retrieved August 21, 2025.
  4. ↑ "Flufenauxirime". PubChem. National Center for Biotechnology Information. Retrieved August 21, 2025.
  5. ↑ "Flufenauxirim". Compendium of Pesticide Common Names. British Crop Production Council. Retrieved August 21, 2025.